diff --git a/biology/spoa/Makefile b/biology/spoa/Makefile
index 41bdf70f51f7..6a1908b3ff73 100644
--- a/biology/spoa/Makefile
+++ b/biology/spoa/Makefile
@@ -25,11 +25,17 @@ USE_LDCONFIG=	yes
 USE_GITHUB=	yes
 GH_ACCOUNT=	rvaser
 
-CMAKE_ON=	BUILD_SHARED_LIBS spoa_optimize_for_portability spoa_build_executable spoa_use_simde spoa_use_simde_nonvec spoa_use_simde_openmp spoa_generate_dispatch
+CMAKE_ON=	BUILD_SHARED_LIBS spoa_optimize_for_portability spoa_build_executable spoa_use_simde spoa_use_simde_nonvec spoa_use_simde_openmp
 CMAKE_OFF=	spoa_optimize_for_native
 
 LDFLAGS+=	-lz -lcpu_features
 
+.include <bsd.port.options.mk>
+
+.if ${ARCH} == amd64 || ${ARCH} == i386
+CMAKE_ARGS+=	-Dspoa_generate_dispatch:BOOL=ON
+.endif
+
 do-test:
 	@cd ${BUILD_WRKSRC} && \
 		${SETENV} ${CONFIGURE_ENV} ${CMAKE_BIN} ${CMAKE_ARGS} -D${PORTNAME}_build_tests:BOOL=ON ${CMAKE_SOURCE_PATH} && \