diff --git a/biology/clustalw/Makefile b/biology/clustalw/Makefile
index 8d8bb796f062..820bfd6888df 100644
--- a/biology/clustalw/Makefile
+++ b/biology/clustalw/Makefile
@@ -6,7 +6,7 @@
 #
 
 PORTNAME=	clustalw
-PORTVERSION=	2.0.12
+PORTVERSION=	2.1
 CATEGORIES=	biology
 MASTER_SITES=	ftp://ftp.ebi.ac.uk/pub/software/clustalw2/%SUBDIR%/ \
 		http://www.clustal.org/download/%SUBDIR%/
diff --git a/biology/clustalw/distinfo b/biology/clustalw/distinfo
index f65695601be4..bd67db762299 100644
--- a/biology/clustalw/distinfo
+++ b/biology/clustalw/distinfo
@@ -1,3 +1,2 @@
-MD5 (clustalw-2.0.12.tar.gz) = 8d0c50ffbe5898b03509aa0a7709f642
-SHA256 (clustalw-2.0.12.tar.gz) = f364fbc9401615b9be91f36562011ca711b840fae4cbfa129b4e13b0b8fc1540
-SIZE (clustalw-2.0.12.tar.gz) = 328025
+SHA256 (clustalw-2.1.tar.gz) = 8c9c54094b9690a86e9e21376b1fc6a7ce2fd3409f5b0175b972c0e1435009ce
+SIZE (clustalw-2.1.tar.gz) = 333808