diff --git a/biology/py-cutadapt/Makefile b/biology/py-cutadapt/Makefile
index 2c87cfeda998..8c86bee19024 100644
--- a/biology/py-cutadapt/Makefile
+++ b/biology/py-cutadapt/Makefile
@@ -1,5 +1,5 @@
 PORTNAME=	cutadapt
-DISTVERSION=	4.8
+DISTVERSION=	4.9
 CATEGORIES=	biology python
 MASTER_SITES=	PYPI
 PKGNAMEPREFIX=	${PYTHON_PKGNAMEPREFIX}
diff --git a/biology/py-cutadapt/distinfo b/biology/py-cutadapt/distinfo
index 1b96e4e7f79a..8e356eb3ce14 100644
--- a/biology/py-cutadapt/distinfo
+++ b/biology/py-cutadapt/distinfo
@@ -1,3 +1,3 @@
-TIMESTAMP = 1716895661
-SHA256 (cutadapt-4.8.tar.gz) = ac852f6b5f2d1147d0d34bef2eaa5879776f81c69a35dd328a701aae39ec6034
-SIZE (cutadapt-4.8.tar.gz) = 251662
+TIMESTAMP = 1718872674
+SHA256 (cutadapt-4.9.tar.gz) = da3b45775b07334d2e2580a7b154d19ea7e872f0da813bb1ac2a4da712bfc223
+SIZE (cutadapt-4.9.tar.gz) = 248837