diff --git a/biology/Makefile b/biology/Makefile
index 2415e6d7a85c..0c097ae77b3b 100644
--- a/biology/Makefile
+++ b/biology/Makefile
@@ -5,6 +5,7 @@
     SUBDIR += R-cran-BiocManager
     SUBDIR += abyss
     SUBDIR += ad2vcf
+    SUBDIR += andi
     SUBDIR += artemis
     SUBDIR += atac-seq
     SUBDIR += augustus
diff --git a/biology/andi/Makefile b/biology/andi/Makefile
new file mode 100644
index 000000000000..ceb195bab1ca
--- /dev/null
+++ b/biology/andi/Makefile
@@ -0,0 +1,32 @@
+PORTNAME=	andi
+DISTVERSIONPREFIX=	v
+DISTVERSION=	0.14-3
+DISTVERSIONSUFFIX=	-g390af15
+CATEGORIES=	biology devel
+
+MAINTAINER=	yuri@FreeBSD.org
+COMMENT=	Efficient estimation of evolutionary distances
+WWW=		https://github.com/EvolBioInf/andi
+
+LICENSE=	GPLv3
+LICENSE_FILE=	${WRKSRC}/COPYING
+
+LIB_DEPENDS=	libdivsufsort.so:math/libdivsufsort \
+		libgsl.so:math/gsl
+
+USES=		autoreconf gmake localbase pkgconfig
+USE_LDCONFIG=	yes
+
+USE_GITHUB=	yes
+GH_ACCOUNT=	EvolBioInf
+
+GNU_CONFIGURE=	yes
+
+OPTIONS_DEFINE=	DOCS
+
+PORTDOCS=	*
+
+PLIST_FILES=	bin/andi \
+		share/man/man1/andi.1.gz
+
+.include <bsd.port.mk>
diff --git a/biology/andi/distinfo b/biology/andi/distinfo
new file mode 100644
index 000000000000..461c52657f4f
--- /dev/null
+++ b/biology/andi/distinfo
@@ -0,0 +1,3 @@
+TIMESTAMP = 1725743879
+SHA256 (EvolBioInf-andi-v0.14-3-g390af15_GH0.tar.gz) = 7373445abd107bbc7fed2f3f01e3dbc34955089cf0690e26beb16bd4014b39ce
+SIZE (EvolBioInf-andi-v0.14-3-g390af15_GH0.tar.gz) = 539569
diff --git a/biology/andi/pkg-descr b/biology/andi/pkg-descr
new file mode 100644
index 000000000000..4d20c8c9b327
--- /dev/null
+++ b/biology/andi/pkg-descr
@@ -0,0 +1,4 @@
+andi is a program for estimating the evolutionary distance between closely
+related genomes. These distances can be used to rapidly infer phylogenies
+for big sets of genomes. Because andi does not compute full alignments,
+it is so efficient that it scales even up to thousands of bacterial genomes.