diff --git a/biology/bifrost/Makefile b/biology/bifrost/Makefile
index 1ca58622a09a..d5afacfb4181 100644
--- a/biology/bifrost/Makefile
+++ b/biology/bifrost/Makefile
@@ -10,6 +10,9 @@ WWW=		https://github.com/pmelsted/bifrost
 LICENSE=	BSD2CLAUSE
 LICENSE_FILE=	${WRKSRC}/LICENSE
 
+# Requires a 64-bit processor
+ONLY_FOR_ARCHS=	aarch64 amd64 powerpc64 powerpc64le riscv64
+
 USES=		cmake
 USE_GITHUB=	yes
 
diff --git a/biology/bifrost/files/patch-CMakeLists.txt b/biology/bifrost/files/patch-CMakeLists.txt
new file mode 100644
index 000000000000..1cf55ff9575f
--- /dev/null
+++ b/biology/bifrost/files/patch-CMakeLists.txt
@@ -0,0 +1,11 @@
+--- CMakeLists.txt.orig	2023-07-16 13:25:06 UTC
++++ CMakeLists.txt
+@@ -20,8 +20,6 @@ if(COMPILATION_ARCH MATCHES "OFF")
+ 	message("Disabling native architecture compilation (including AVX2)")
+ else(COMPILATION_ARCH MATCHES "OFF")
+ 	message("Compilation architecture: ${COMPILATION_ARCH}")
+-	set(CMAKE_C_FLAGS "${CMAKE_C_FLAGS} -march=${COMPILATION_ARCH}")
+-	set(CMAKE_CXX_FLAGS "${CMAKE_CXX_FLAGS} -march=${COMPILATION_ARCH}")
+ endif(COMPILATION_ARCH MATCHES "OFF")
+ 
+ if(ENABLE_AVX2 MATCHES "OFF")