diff --git a/devel/grpc/Makefile b/devel/grpc/Makefile
index 0aad80558e16..de0629308967 100644
--- a/devel/grpc/Makefile
+++ b/devel/grpc/Makefile
@@ -3,6 +3,7 @@
 PORTNAME=	grpc
 PORTVERSION=	1.38.1
 DISTVERSIONPREFIX=	v
+PORTREVISION=	1
 PORTEPOCH=	2
 CATEGORIES=	devel
 
@@ -38,4 +39,11 @@ USE_LDCONFIG=	yes
 PLIST_SUB=	SHLIB_MAJOR=${PORTVERSION:R} \
 		SHLIB_MINOR=${PORTVERSION:E}
 
-.include <bsd.port.mk>
+.include <bsd.port.pre.mk>
+
+# Remove openssl from grpc.pc because we do not ship openssl.pc in base system
+.if ${SSL_DEFAULT} == base
+EXTRA_PATCHES+=	${PATCHDIR}/extra-patch-CMakeLists.txt
+.endif
+
+.include <bsd.port.post.mk>
diff --git a/devel/grpc/files/extra-patch-CMakeLists.txt b/devel/grpc/files/extra-patch-CMakeLists.txt
new file mode 100644
index 000000000000..07020b8e727b
--- /dev/null
+++ b/devel/grpc/files/extra-patch-CMakeLists.txt
@@ -0,0 +1,13 @@
+Remove openssl from grpc.pc because we do not ship openssl.pc in base system
+
+--- CMakeLists.txt.orig	2021-06-19 00:53:16 UTC
++++ CMakeLists.txt
+@@ -15696,7 +15696,7 @@ generate_pkgconfig(
+   "gRPC"
+   "high performance general RPC framework"
+   "${gRPC_CORE_VERSION}"
+-  "gpr openssl absl_base absl_bind_front absl_flat_hash_map absl_inlined_vector absl_memory absl_optional absl_status absl_statusor absl_str_format absl_strings absl_synchronization absl_time"
++  "gpr absl_base absl_bind_front absl_flat_hash_map absl_inlined_vector absl_memory absl_optional absl_status absl_statusor absl_str_format absl_strings absl_synchronization absl_time"
+   "-lgrpc -laddress_sorting -lre2 -lupb -lcares -lz"
+   ""
+   "grpc.pc")