diff --git a/biology/avida/Makefile b/biology/avida/Makefile
index 79ba36776c62..055fcba07661 100644
--- a/biology/avida/Makefile
+++ b/biology/avida/Makefile
@@ -21,7 +21,6 @@ PORTDOCS=	*
 PLIST_FILES=	${BIN_FILES:S|^|bin/|} \
 		${BIN_FILES:S|^|lib/${PORTNAME}/|} \
 		${DATA_FILES:S|^|lib/${PORTNAME}/|}
-PLIST_DIRS=	lib/${PORTNAME}
 
 BIN_FILES=	avida avida-viewer
 DATA_FILES=	analyze.cfg avida.cfg default-gx.org \
diff --git a/biology/blat/Makefile b/biology/blat/Makefile
index 87497e84cc90..c095e0c3cbcf 100644
--- a/biology/blat/Makefile
+++ b/biology/blat/Makefile
@@ -32,8 +32,6 @@ PORTDOCS=	README
 PLIST_FILES=	${EXECUTABLES:S,^,bin/,} \
 		lib/blat/webBlat/webBlat \
 		lib/blat/webBlat/install.txt
-PLIST_DIRS=	lib/blat/webBlat \
-		lib/blat
 
 EXECUTABLES=	blat faToNib faToTwoBit gfClient gfServer nibFrag \
 		pslPretty pslReps pslSort twoBitInfo twoBitToFa
diff --git a/biology/linux-foldingathome/Makefile b/biology/linux-foldingathome/Makefile
index 8f399724c3cf..5f2eaadd7c07 100644
--- a/biology/linux-foldingathome/Makefile
+++ b/biology/linux-foldingathome/Makefile
@@ -17,7 +17,6 @@ ONLY_FOR_ARCHS=	i386 amd64
 REINPLACE_ARGS=
 PLIST_FILES=	share/${PORTNAME}/${DISTNAME}${EXTRACT_SUFX} \
 		bin/FoldingAtHome
-PLIST_DIRS=	share/${PORTNAME}
 
 do-extract:
 	${MKDIR} ${WRKSRC}
diff --git a/biology/povchem/Makefile b/biology/povchem/Makefile
index 28b0b3d64ebe..64823160e0eb 100644
--- a/biology/povchem/Makefile
+++ b/biology/povchem/Makefile
@@ -25,7 +25,6 @@ CPPFLAGS+=	-DDATADIR=\"${DATADIR}\" \
 		-DSYSCONFDIR=\"${PREFIX}/etc\"
 
 PLIST_FILES=	bin/povchem etc/povchem.cfg %%DATADIR%%/periodic.tab
-PLIST_DIRS=	%%DATADIR%%
 
 post-extract:
 	@(cd ${DISTDIR}/${DIST_SUBDIR} && ${TAR} -cf - ${DISTFILES}) | \
diff --git a/biology/seaview/Makefile b/biology/seaview/Makefile
index 5a4ce3057422..1c832337c600 100644
--- a/biology/seaview/Makefile
+++ b/biology/seaview/Makefile
@@ -29,7 +29,6 @@ ALL_TARGET=	${PORTNAME}
 
 PLIST_FILES=	bin/seaview man/man1/seaview.1.gz %%DATADIR%%/seaview.html \
 		share/pixmaps/seaview.xpm
-PLIST_DIRS=	%%DATADIR%%
 
 DESKTOP_ENTRIES="SeaView" "" "${PREFIX}/share/pixmaps/seaview.xpm" "seaview" \
 		"Biology;Science;" true
diff --git a/biology/ssaha/Makefile b/biology/ssaha/Makefile
index 32c91386444a..60c536f91053 100644
--- a/biology/ssaha/Makefile
+++ b/biology/ssaha/Makefile
@@ -22,7 +22,6 @@ ALL_TARGET=	ssaha
 
 PLIST_FILES=	bin/ssaha %%DATADIR%%/testSSAHA.csh \
 		${DATA_FILES:S,^,%%DATADIR%%/,}
-PLIST_DIRS=	%%DATADIR%%
 
 DATA_FILES=	test.fasta test_extract.fasta test_filter.fail \
 		test_filter.fastq test_protein.fasta README
diff --git a/biology/wise/Makefile b/biology/wise/Makefile
index 387a15bf7293..f6385382960b 100644
--- a/biology/wise/Makefile
+++ b/biology/wise/Makefile
@@ -23,7 +23,6 @@ SUB_FILES=	pkg-message
 PORTDOCS=	*
 PORTEXAMPLES=	*
 PLIST_FILES=	${BINFILES:S,^,bin/,} ${DATAFILES:S,^,%%DATADIR%%/,}
-PLIST_DIRS=	%%DATADIR%%
 
 #
 # Actually want an 'ALL_TARGET = all perl' which then requires