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21 lines
1.3 KiB
Plaintext
21 lines
1.3 KiB
Plaintext
PhyML is a software that estimates maximum likelihood phylogenies from
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alignments of nucleotide or amino acid sequences. It provides a wide
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range of options that were designed to facilitate standard phylogenetic
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analyses. The main strengths of PhyML lies in the large number of
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substitution models coupled to various options to search the space of
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phylogenetic tree topologies, going from very fast and efficient methods
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to slower but generally more accurate approaches. It also implements two
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methods to evaluate branch supports in a sound statistical framework
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(the non-parametric bootstrap and the approximate likelihood ratio
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test). PhyML was designed to process moderate to large data sets. In
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theory, alignments with up to 4,000 sequences 2,000,000 character-long
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can analyzed. In practice however, the amount of memory required to
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process a data set is proportional of the product of the number of
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sequences by their length. Hence, a large number of sequences can only
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be processed provided that they are short. Also, PhyML can handle long
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sequences provided that they are not numerous. With most standard
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personal computers, the "comfort zone" for PhyML generally lies around 3
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to 500 sequences less than 2,000 character long.
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WWW: https://github.com/stephaneguindon/phyml
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