diff --git a/pkgs/development/python-modules/pymonoprice/default.nix b/pkgs/development/python-modules/pymonoprice/default.nix
new file mode 100644
index 000000000000..d1e878ab473e
--- /dev/null
+++ b/pkgs/development/python-modules/pymonoprice/default.nix
@@ -0,0 +1,41 @@
+{
+  lib,
+  buildPythonPackage,
+  fetchFromGitHub,
+  pyserial,
+  pyserial-asyncio-fast,
+  pytestCheckHook,
+  setuptools,
+}:
+
+buildPythonPackage rec {
+  pname = "pymonoprice";
+  version = "0.5";
+  pyproject = true;
+
+  src = fetchFromGitHub {
+    owner = "etsinko";
+    repo = "pymonoprice";
+    tag = version;
+    hash = "sha256-kyFOWG/Jvn+h9ludzd2Zul9/lkwPxReH76nnDIGD+fM=";
+  };
+
+  build-system = [ setuptools ];
+
+  dependencies = [
+    pyserial
+    pyserial-asyncio-fast
+  ];
+
+  nativeCheckInputs = [ pytestCheckHook ];
+
+  pythonImportsCheck = [ "pymonoprice" ];
+
+  meta = {
+    description = "Python 3 interface implementation for Monoprice 6 zone amplifier";
+    homepage = "https://github.com/etsinko/pymonoprice";
+    changelog = "https://github.com/etsinko/pymonoprice/releases/tag/${version}";
+    license = lib.licenses.mit;
+    maintainers = [ lib.maintainers.jamiemagee ];
+  };
+}
diff --git a/pkgs/servers/home-assistant/component-packages.nix b/pkgs/servers/home-assistant/component-packages.nix
index a1a5824877c2..3fec8e07ec1e 100644
--- a/pkgs/servers/home-assistant/component-packages.nix
+++ b/pkgs/servers/home-assistant/component-packages.nix
@@ -3693,7 +3693,8 @@
       ];
     "monoprice" =
       ps: with ps; [
-      ]; # missing inputs: pymonoprice
+        pymonoprice
+      ];
     "monzo" =
       ps: with ps; [
         monzopy
@@ -7319,6 +7320,7 @@
     "modem_callerid"
     "modern_forms"
     "mold_indicator"
+    "monoprice"
     "monzo"
     "moon"
     "mopeka"
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 337c903a6e4b..a00f7fcc14aa 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -13277,6 +13277,8 @@ self: super: with self; {
 
   pymongo-inmemory = callPackage ../development/python-modules/pymongo-inmemory { };
 
+  pymonoprice = callPackage ../development/python-modules/pymonoprice { };
+
   pymoo = callPackage ../development/python-modules/pymoo { };
 
   pymorphy2 = callPackage ../development/python-modules/pymorphy2 { };