diff --git a/pkgs/development/libraries/boost/cmake-paths-188.patch b/pkgs/development/libraries/boost/cmake-paths-188.patch
new file mode 100644
index 000000000000..0abb97111dcf
--- /dev/null
+++ b/pkgs/development/libraries/boost/cmake-paths-188.patch
@@ -0,0 +1,21 @@
+diff --color -ur boost_1_88_0-unpatched/tools/boost_install/boost-install.jam boost_1_88_0/tools/boost_install/boost-install.jam
+--- boost_1_88_0-unpatched/tools/boost_install/boost-install.jam	2025-07-29 21:46:33.010181683 +0800
++++ boost_1_88_0/tools/boost_install/boost-install.jam	2025-07-29 21:47:34.346642613 +0800
+@@ -794,7 +794,7 @@
+         ""
+         "# Compute the include and library directories relative to this file."
+         ""
+-        "get_filename_component(_BOOST_CMAKEDIR \"${CMAKE_CURRENT_LIST_DIR}/../\" REALPATH)"
++        "get_filename_component(_BOOST_REAL_CMAKEDIR \"${CMAKE_CURRENT_LIST_DIR}/../\" REALPATH)"
+         : true ;
+ 
+     if [ path.is-rooted $(cmakedir) ]
+@@ -813,6 +813,8 @@
+             "  unset(_BOOST_CMAKEDIR_ORIGINAL)"
+             "endif()"
+             ""
++	    "# Assume that the installer actually did know where the libs were to be installed"
++            "get_filename_component(_BOOST_CMAKEDIR \"$(cmakedir-native)\" REALPATH)"
+             : true ;
+     }
+ 
diff --git a/pkgs/development/libraries/boost/generic.nix b/pkgs/development/libraries/boost/generic.nix
index aa6f1059799c..9d09f79243fa 100644
--- a/pkgs/development/libraries/boost/generic.nix
+++ b/pkgs/development/libraries/boost/generic.nix
@@ -170,6 +170,7 @@ stdenv.mkDerivation {
       lib.versionOlder version "1.88" && stdenv.hostPlatform.isDarwin
     ) ./darwin-no-system-python.patch
     ++ lib.optional (lib.versionOlder version "1.88") ./cmake-paths-173.patch
+    ++ lib.optional (lib.versionAtLeast version "1.88") ./cmake-paths-188.patch
     ++ lib.optional (version == "1.77.0") (fetchpatch {
       url = "https://github.com/boostorg/math/commit/7d482f6ebc356e6ec455ccb5f51a23971bf6ce5b.patch";
       relative = "include";