diff --git a/pkgs/development/ocaml-modules/rfc7748/default.nix b/pkgs/development/ocaml-modules/rfc7748/default.nix
index b15ad8684eab..0cc59fa3e7c5 100644
--- a/pkgs/development/ocaml-modules/rfc7748/default.nix
+++ b/pkgs/development/ocaml-modules/rfc7748/default.nix
@@ -1,6 +1,7 @@
 { lib
 , buildDunePackage
 , fetchFromGitHub
+, fetchpatch
 , ocaml
 
 , ounit
@@ -18,6 +19,12 @@ buildDunePackage rec {
     sha256 = "sha256-mgZooyfxrKBVQFn01B8PULmFUW9Zq5HJfgHCSJSkJo4=";
   };
 
+  # Compatibility with OCaml 5.0
+  patches = fetchpatch {
+    url = "https://github.com/burgerdev/ocaml-rfc7748/commit/f66257bae0317c7b24c4b208ee27ab6eb68460e4.patch";
+    hash = "sha256-780yy8gLOwwf7xIKIIIaoGpDPcY7+dZ0jPS4nrkH2s8=";
+  };
+
   minimalOCamlVersion = "4.05";
 
   propagatedBuildInputs = [ zarith ];