diff --git a/pkgs/applications/science/biology/seqtk/default.nix b/pkgs/applications/science/biology/seqtk/default.nix
index 417bec9c062f..856248de917d 100644
--- a/pkgs/applications/science/biology/seqtk/default.nix
+++ b/pkgs/applications/science/biology/seqtk/default.nix
@@ -19,14 +19,13 @@ stdenv.mkDerivation rec {
 
   buildInputs = [ zlib libdeflate isa-l ];
 
-  makeFlags = [ "CC=cc" ];
+  makeFlags = [
+    "CC:=$(CC)"
+    "BINDIR=$(out)/bin"
+  ];
 
-  installPhase = ''
-    runHook preInstall
-
-    install -Dm755 -t $out/bin seqtk
-
-    runHook postInstall
+  preInstall = ''
+    mkdir -p "$out/bin"
   '';
 
   meta = with lib; {