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and EST Sequences. PR: ports/103651 Submitted by: Bob Zimmermann <rpz at cse.wustl.edu>
13 lines
679 B
Plaintext
13 lines
679 B
Plaintext
A standalone program for mapping and aligning cDNA sequences to a
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genome. The program maps and aligns a single sequence with minimal
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startup time and memory requirements, and provides fast batch
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processing of large sequence sets. The program generates accurate
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gene structures, even in the presence of substantial polymorphisms
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and sequence errors, without using probabilistic splice site models.
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Methodology underlying the program includes a minimal sampling
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strategy for genomic mapping, oligomer chaining for approximate
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alignment, sandwich DP for splice site detection, and microexon
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identification with statistical significance testing.
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WWW: http://www.gene.com/share/gmap
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